The Reds were dumped out of Europe on penalties after losing 1-0 to the French side - with the tie finishing level at 1-1 on aggregate - in Tuesday's (11.03.25) second leg and the coach argued that his team were unlucky to be on the wrong end of the result.
Slot said: "It was the best game of football I was ever involved in. Incredible performance, especially if you compare it with last week. We were creating chances, and then we were 1-0 down. Maybe we ran out of luck after last week.
"For me, it felt like we deserved more than being 1-0 down. We played the perfect game except for scoring a goal. It was similar to PSG last week, where they played the perfect game. And then in extra time they were maybe a little bit better.
"It came down to penalties and we, as Dutch, know how to lose them.
"For now, everyone should be disappointed ... I know these players, they’re resilient. It had everyone you wanted from a game. From a Liverpool perspective, we could have at least wanted a draw after 90 minutes."
Slot also claimed that it felt "unfair" that they had been handed a tough tie against PSG in the last 16 despite finishing top of the league phase.
The manager said: "It feels unfair that we topped the table and then faced such a strong team as PSG. We now have a League Cup final and nine Premier League games to go."
Liverpool captain Virgil van Dijk shared his manager's disappointment and believed that the team played far better in defeat than they did in winning last week's first leg in the French capital.
The defender said: "It was a totally different Liverpool to what we showed in Paris. But penalties… that is the reality.
"I think even in the first half we created dangerous moments. But it came down to penalties. We were pretty good today. You want to go as far as possible."